Paolo Vineis (born 10 October 1951, in Alba) is an Italian professor of Environmental Epidemiology at

Imperial College London Imperial College London (legally Imperial College of Science, Technology and Medicine) is a public research university in London, United Kingdom. Its history began with Prince Albert, consort of Queen Victoria, who developed his vision for a cu ...

. His main work is on the impact of environmental changes (including air pollution and climate change) on human health and molecules. This includes the use of

omics The branches of science known informally as omics are various disciplines in biology whose names end in the suffix '' -omics'', such as genomics, proteomics, metabolomics, metagenomics, phenomics and transcriptomics. Omics aims at the collect ...

technologies in epidemiological studies, that is the quantitative measurement of global sets of molecules in biological samples using high-throughput techniques, in combination with advanced biostatistics and bioinformatics tools. In particular, the study of epigenomic changes in DNA is currently one of the most promising fields for the identification of long-term environmental fingerprints. The development of the concept of

exposome An environmental factor, ecological factor or eco factor is any factor, abiotic or biotic, that influences living organisms. Abiotic factors include ambient temperature, amount of sunlight, and pH of the water soil in which an organism lives. Bi ...

(with Chris Wild, Director of the

World Health Organization The World Health Organization (WHO) is a specialized agency of the United Nations responsible for international public health. The WHO Constitution states its main objective as "the attainment by all peoples of the highest possible level of ...

International Agency for Research on Cancer The International Agency for Research on Cancer (IARC; french: Centre International de Recherche sur le Cancer, CIRC) is an intergovernmental agency forming part of the World Health Organization of the United Nations. Its role is to conduct and ...

, and Stephen Rappaport and Martyn Smith of

University of California, Berkeley The University of California, Berkeley (UC Berkeley, Berkeley, Cal, or California) is a public land-grant research university in Berkeley, California. Established in 1868 as the University of California, it is the state's first land-grant u ...

's School of Public Health), led to Professor Vineis being awarded a grant from the

European Commission The European Commission (EC) is the executive of the European Union (EU). It operates as a cabinet government, with 27 members of the Commission (informally known as "Commissioners") headed by a President. It includes an administrative body ...

(

Seventh Framework Programme The Framework Programmes for Research and Technological Development, also called Framework Programmes or abbreviated FP1 to FP9, are funding programmes created by the European Union/European Commission to support and foster research in the Europe ...

) in 2012 on

research (EXPOsOMICS). The

refers to the totality of internal and external exposures which interact at a cellular and systems level to generate a metabolic/ molecular signature which can be used to gain new understanding of the transition from health to disease. Paolo Vineis is also the coordinator of the Horizon 2020 LIFEPATH project, whose aim is to understand the determinants of diverging ageing pathways among individuals belonging to different socio-economic groups. This is achieved by integrating social science approaches with biology, using omics measurements (particularly epigenomics). Paolo Vineis is also the director of the Unit of Molecular and Genetic Epidemiology, Italian Institute of Genomic Medicine (IIGM),

Turin Turin ( , Piedmontese: ; it, Torino ) is a city and an important business and cultural centre in Northern Italy. It is the capital city of Piedmont and of the Metropolitan City of Turin, and was the first Italian capital from 1861 to 1865. The ...

, Italy. Professor Vineis has published many research articles on environmental risks and has written several books on health, causality and the ethics of health care.

Selected publications

Selected articles

*Vineis P, Bartsch H, Caporaso N, Harrington AM, Kadlubar FF, Landi MT, Malaveille C, Shields PG, Skipper P, Talaska G, et al. ''Genetically based N-acetyltransferase metabolic polymorphism and low-level environmental exposure to carcinogens''. Nature. 1994 May 12;369(6476):154-6 *Berwick M, and Vineis P. ''Markers of DNA repair and susceptibility to cancer in humans: an epidemiologic review.'' Journal of the National Cancer Institute 92, no. 11 (2000): 874-897. *Vineis P., Alavanja M., Buffler P., Fontham E., Franceschi S., Gao, Y.T., Gupta P.C., Hackshaw A., Matos E., Samet J., Sitas F., Smith J., Stayner L., Straif K., Thun MJ., Wichmann HE, Wu AH., Zaridze D., Peto R., Doll R. 2004. ''Tobacco and cancer: recent epidemiological evidence.'' Journal of the National Cancer Institute, 96(2), pp. 99–106. *Vineis P, Khan A. ''Climate change-induced salinity threatens health''. Science. 2012 Nov 23;338(6110):1028-9. *Shenker NS, Polidoro S, van Veldhoven K, Sacerdote C, Ricceri F, Birrell MA, Belvisi MG, Brown R, Vineis P, Flanagan JM. ''Epigenome-wide association study in the European Prospective Investigation into Cancer and Nutrition (EPIC-Turin) identifies novel genetic loci associated with smoking''. Hum Mol Genet. 2013 Mar 1;22(5):843-51 *Khan AE, Scheelbeek PF, Shilpi AB, Chan Q, Mojumder SK, Rahman A, Haines A, Vineis P. ''Salinity in drinking water and the risk of (pre)eclampsia and gestational hypertension in coastal Bangladesh: a case-control study''. PLoS One. 2014 Sep 30;9(9):e108715 *Vineis P, Wild CP. ''Global cancer patterns: causes and prevention''. Lancet. 2014; 383(9916): 549-57. *Vineis P. ''Public health and the common good''. J Epidemiol Community Health. 2014 Feb;68(2):97-100. * Vineis P, Stringhini S, Porta M. Environ Res. ''The environmental roots of non-communicable diseases (NCDs) and the epigenetic impacts of globalization''. 2014 Aug;133:424-30. *Fasanelli F, Baglietto L, Ponzi E, Guida F, Campanella G, Johansson M, Grankvist K, Johansson M, Assumma MB, Naccarati A, Chadeau-Hyam M, Ala U, Faltus C, Kaaks R, Risch A, De Stavola B, Hodge A, Giles GG, Southey MC, Relton CL, Haycock PC, Lund E, Polidoro S, Sandanger TM, Severi G, Vineis P. ''Hypomethylation of smoking-related genes is associated with future lung cancer in four prospective cohorts.'' Nature Communications. 2015 Dec 15;6:10192. *Bray F, Jemal A, Torre LA, Forman D, Vineis P. ''Long-term Realism and Cost-effectiveness: Primary Prevention in Combatting Cancer and Associated Inequalities Worldwide.'' J Natl Cancer Inst. 2015 Sep 30;107(12):djv273. *Stringhini S, Polidoro S, Sacerdote C, Kelly RS, van Veldhoven K, Agnoli C, Grioni S, Tumino R, Giurdanella MC, Panico S, Mattiello A, Palli D, Masala G, Gallo V, Castagné R, Paccaud F, Campanella G, Chadeau-Hyam M, Vineis P. ''Life-course socioeconomic status and DNA methylation of genes regulating inflammation.'' Int J Epidemiol. 2015 Aug;44(4):1320-30 *Vineis P, Saracci R. ''Conflicts of interest matter and awareness is needed.'' J Epidemiol Community Health. 2015 Oct;69(10):1018-20.143

Books

*Vineis Paolo. Health without borders. Epidemics in the era of globalization. Springer International Publishing AG. 2017. *Vineis, Paolo. Salute senza confini: le epidemie al tempo della globalizzazione. Torino: Codice, 2014. *Vineis, Paolo, and Roberto Satolli. I due dogmi: oggettività della scienza e integralismo etico. Milano: Feltrinelli, 2009. *Vineis, Paolo, and Nerina Dirindin. In buona salute: dieci argomenti per difendere la sanità pubblica. Torino: Einaudi, 2004. *Vineis, Paolo. Nel crepuscolo della probabilità: la medicina tra scienza ed etica. Torino: Einaudi, 1999

References

External links

*http://www.iigm.it/site/anteprima.php?l=ENG
Molecular and Genetic Epidemiology, HuGeFEXPOsOMICS, About usLIFEPATH, Healthy ageing for all
{{DEFAULTSORT:Vineis, Paolo Living people Academics of Imperial College London 1951 births